Influences of 5-HT2 receptor antagonists on imipramine-induced decreases in immobility in forced swimming test
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چکیده
منابع مشابه
The 5-HT2 receptor antagonist reduces immobility of mice treated with the atypical antidepressant mianserin in the forced swimming test.
Effects of co-administration with the 5-HT(2) receptor antagonist LY 53857 and the antidepressant mianserin on immobility time in the forced swimming test were investigated in mice. Mianserin did not affect the immobility time at ranges from 1-10 mg/kg, although it elicited anti-immobility effects at 20 mg/kg. Co-administration of the 5-HT(2) receptor antagonist LY 53857 and a subactive dose of...
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Moclobemide is a selective and reversible monoamine oxidase-A inhibitor, which is used as an antidepressant. Three moclobemide analogues were synthesized by replacing moclobemide phenyl ring with substituted imidazoles. So, N-[(4-morpholinyl) ethyl)]-1-benzyl-2-(alkylthio)-1H-imidazole-5-carboxamides (7a-c) were synthesized and studied for the antidepressant activity using forced swimming test ...
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Moclobemide is a selective and reversible monoamine oxidase-A inhibitor, which is used as an antidepressant. Three moclobemide analogues were synthesized by replacing moclobemide phenyl ring with substituted imidazoles. So, N-[(4-morpholinyl) ethyl)]-1-benzyl-2-(alkylthio)-1H-imidazole-5-carboxamides (7a-c) were synthesized and studied for the antidepressant activity using forced swimming test ...
متن کاملEffect of Withania somnifera on forced swimming test induced immobility in mice and its interaction with various drugs.
The objective of the present study was to evaluate the antidepressant action of Withania somnifera (WS) as well as its interaction with the conventional antidepressant drugs and to delineate the possible mechanism of its antidepressant action using forced swimming model in mice. Effect of different doses of WS, fluoxetine and imipramine were studied on forced swimming test induced mean immobili...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 2000
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)47951-1